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Financement de l’UE (15 M €) : Recommandations personnalisées pour les maladies neurodégénératives Hor01/12/2018 Programme de recherche et d'innovation de l'UE « Horizon »
Vue d’ensemble
Texte
Recommandations personnalisées pour les maladies neurodégénératives
The annual worldwide cost of Alzheimer’s dementia was 777.81 billion Euro in 2015. This number will rise to 7.41 trillion Euro in 2050. Early diagnosis would save up to $7.9 trillion in medical and care costs by 2050 in the US alone. However, the emergent pathology is highly variable across people, necehighly variable across people, necessitating individualized diagnostics and interventions. The VirtualBrainCloud addresses this by bridging the gap between computational neuroscience and subcellular systems biology, integrating both research streams into a unifying computational model that supports personalized diagnostics and treatments in NDD. TheVirtualBrainCloud not only integrates existing software tools, it also merges the efforts of two big EU initiatives, namely The Virtual Brain large scale simulation platform of the EU Flagship Human Brain Project and IMI-EPAD initiative (European prevention of Alzheimer’s dementia consortium). VirtualBrainCloud will develop and validate a decision support system that provides access to high quality multi-disciplinary data for clinical practice. The result will be a cloud-based brain simulation platform to support personalized diagnostics and treatments in NDD. The EU PRACE (Partnership for Advanced Computing in Europe) initiative, will provide the required computing infrastructure. The VirtualBrainCloud will develop robust solutions for legal and ethical matters by interacting with EU projects such as European Open Science Cloud (EOSC), ‘cloud4health’, Alzheimer’s Europe patient organizations and ELIXIR, an organization that manages and safeguards EU research data. Our software developers have already produced highly successful brain simulation and clinical decision support tools. The resulting software will be a cloud based computational modeling system that is tailored to the individual, and bridges multiple scales to identify key mechanisms that predict NDD progression and serves as Precision Decision Support System.
| Alzheimer Europe | 176 500 € |
| CHARITE - UNIVERSITAETSMEDIZIN BERLIN | 1 985 750 € |
| CODEBOX GmbH | 148 750 € |
| Centre National de la Recherche Scientifique Cnrs | 0,00 € |
| 422 750 € | |
| Eodyne Systems SL | 407 500 € |
| FORSCHUNGSZENTRUM JULICH GmbH | 3 736 729 € |
| FRAUNHOFER GESELLSCHAFT ZUR FORDERUNG DER ANGEWANDTEN FORSCHUNG e. V. | 1 868 750 € |
| Fundacio Institut de Bioenginyeria de Catalunya | 635 663 € |
| HELSINGIN YLIOPISTO | 840 280 € |
| Institut National de Recherche en Informatique et Automatique | 324 435 € |
| Institut National de la Sante et de la Recherche Medicale | 0,00 € |
| Institut du Cerveau et de la Moelle Epiniere | 1 188 750 € |
| 51 275 € | |
| TP21 GmbH | 376 250 € |
| The Chancellor, Masters and Scholars of the University of Oxford | 462 430 € |
| Universidad Complutense de Madrid | 396 250 € |
| Universita Degli Studi DI Genova | 425 091 € |
| Universitat Wien | 462 098 € |
| Universite d'AIX Marseille | 1 107 093 € |
https://cordis.europa.eu/project/id/826421
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