Moteur de recherche d’entreprises européennes
Financement de l’UE (3 733 515 €) : Démêler les principes de la signalisation cellulaire médiée par PDZ Hor01/09/2016 Programme de recherche et d'innovation de l'UE « Horizon »
Vue d’ensemble
Texte
Démêler les principes de la signalisation cellulaire médiée par PDZ
PDZnet will create an innovative European PhD training network focusing on unraveling PDZ domain-mediated signaling networks. The emphasis will be on signaling nodes essential for the development of cancer and diseases of the nervous system, conditions that affect millions of Europeans and are major societal challenges. PDZ domains are protein and lipid recognizing modules that play a central role in trafficking and organizing diverse cell signaling ass????ies, thereby allowing information to be transmitted from receptors, ion channels and transporters in the cell membrane. PDZ domain mediated interactions are emerging as conceptually novel and promising drug targets, with exciting opportunities for the development of novel therapies, especially within cancer and brain diseases. We will establish a European multidisciplinary platform integrating a plethora of complementary life science disciplines that range from chemical development of inhibitors to studies in live animals. The network encompasses 8 academic and 2 industrial beneficiaries as well as one industrial and one academic partner, which are all committed to promote frontline research, innovation and educational activities within the study of PDZ domain-mediated signal transduction pathways related to brain diseases and cancer. This interdisciplinary network will establish an outstanding training opportunity for Early Stage Researchers, who will be integrated in projects unraveling intracellular PDZ domain interactomes to provide pertinent information for discovering drug-related interactions. In a comprehensive and integrated training effort, involving a combination of scientific and transferable skills, the students will receive an interdisciplinary, intersectoral and innovative doctoral training from experienced industrial and academic leaders in well-reputed European Institutions.
| Centre Europeen de Recherche en Biologie et Medecine | 262 876 € |
| 249 216 € | |
| Institut National de la Sante et de la Recherche Medicale | 307 418 € |
| Institut Pasteur | 262 876 € |
| JOHANN WOLFGANG GOETHE-UNIVERSITAET FRANKFURT AM MAIN | 249 216 € |
| Kobenhavns Universitet | 580 164 € |
| Novo Nordisk A/S | 580 164 € |
| SYSTASY BIOSCIENCE GmbH | 456 205 € |
| Universita Degli Studi DI Roma LA Sapienza | 258 061 € |
| Uppsala Universitet | 527 319 € |
https://cordis.europa.eu/project/id/675341
Cette annonce se réfère à une date antérieure et ne reflète pas nécessairement l’état actuel.
Les visualisations de "Centre Europeen de Recherche en Biologie et Medecine - Financement de l’UE (3 733 515 €) : Démêler les principes de la signalisation cellulaire médiée par PDZ"
sont mis à disposition par
North Data
et peuvent être réutilisées selon les termes de la licence
Creative Commons CC-BY.
