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Financement de l’UE (11,6 M €) : Réseau latino-américain de préparation au virus Zika Hor01/10/2016 Programme de recherche et d'innovation de l'UE « Horizon »

Texte

Réseau latino-américain de préparation au virus Zika

The ZikaPLAN initiative combines the strengths of 25 partners in Latin America, North America, Africa, Asia, and various centres in Europe to address the urgent research gaps (WP 1-8) in Zika, identifying short-and long term solutions (WP 9-10) and building a sustainable Latin-American EID Preparedness and Response capacity (WP 11-12). 
 We will conduct clinical studies to further refine the full spectrum and risk factors of congenital Zika syndrome (including neurodevelopmental milestones in the first 3 years of life), and delineate neurological complications associated with Zika due to direct neuroinvasion and immune-mediated responses. Laboratory based research to unravel neurotropism, investigate the role of sexual transmission, determinants of severe disease, and viral fitness will envelop the clinical studies.
 Burden of disease and modelling studies will assemble a wealth of data including a longitudinal cohort study of 17,000 subjects aged 2-59 in 14 different geographic locations in Brazil over 3 years. Data driven vector control and vaccine modelling as well as risk assessments on geographic spread of Zika will form the foundation for evidence-informed policies. The Platform for Diagnostics Innovation and Evaluation will develop novel ZIKV diagnostic tests in accordance with WHO Target Product Profiles. Our global network of laboratory and clinical sites with well-characterized specimens is set out to accelerate the evaluation of the performance of such tests. 
 Based on qualitative research, we will develop supportive, actionable messages to affected communities, and develop novel personal protective measures. Our final objective is for the Zika outbreak response effort to grow into a sustainable Latin-American network for emerging infectious diseases research preparedness. To this end we will engage in capacity building in laboratory and clinical research, collaborate with existing networks to share knowledge and tackle regulatory and other bottlenecks.


?????????? ??????? ?????????? ?????? ???????????? ?????? ????????? ?? ??????????? ?????????? 191 150 €
Erasmus Universitair Medisch Centrum Rotterdam 649 825 €
Fondation Merieux 801 250 €
Fundacao DE Apoio A Universidade DE SAO Paulo 100 076 €
???????? ??????? ???? 169 348 €
???????? ???????????? ?? ?????????? 1 244 671 €
????????? ??????????? ??? ????? 274 990 €
Imaccess SAS 0,00 €
Institut Pasteur 183 203 €
Institut Pasteur DE Dakar 99 763 €
????????? ???????? 454 688 €
????????? ?? ???????? ???????? ????? ????? 94 500 €
Instituut Voor Tropische Geneeskunde 244 500 €
????????????? ??????? ????????? 0,00 €
Katholieke Universiteit Leuven 96 750 €
?? ????? ????????? ??? ??????? ??? ?????????? 60 615 €
?????? ?????? ?? ??????? ??? ???????? ???????? ????? ??????? 1 958 648 €
Queen Mary University of London 37 651 €
SAS les Pensieres 0,00 €
SCHWEIZERISCHES TROPEN UND PUBLIC HEALTH INSTITUT 0,00 €
St George's Hospital Medical School 38 920 €
??? ?????????? ?? ????? ???????? ?? ?????? ???? 106 250 €
The Chancellor, Masters and Scholars of the University of Oxford 909 446 €
The University of Liverpool 1 030 645 €
Umea Universitet 1 680 619 €
??????????? ??? ????? 117 711 €
University of Glasgow 625 000 €
University of Ulster 396 156 €

https://cordis.europa.eu/project/id/734584

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